CV Wolfram Kunz

KUNZ, Wolfram S., Prof. Dr. rer. nat.

Born 29.07. 1956

Division of Neurochemistry,

Department of Experimental Epileptology and Cognition Research

University Bonn Medical Center and Life & Brain Center, University Bonn
Sigmund-Freud-Str. 25
53105 Bonn

Tel.:     +49 228-6885 290

Fax:     +49 228-6885 236

Email:  wolfram.kunz@ukb.uni-bonn.de

Current position: W2 professor of Neurochemistry

 

Education and Degree
1975–1980 Student of Biophysics, Kharkov University and Moscow State University
1980–1983 PhD student, Department of Bioenergetics, Moscow State University

 

Scientific Degrees
1980 MSc (with distinction), Kharkov University (Ukraine), supervisor A.A. Konstantinov
1983 PhD (Biochemistry), Moscow State University (Russia), supervisor V.P. Skulachev
1992 Habilitation thesis (Biochemistry), Halle University
1999 Re-habilitation, venia legendi for Neurochemistry, Bonn University

 

Professional career after graduation
Since 2008 W2 Professor of Neurochemistry at Dept. Epileptology, Bonn University, School of Medicine
2007 Call for a W3 Professorship of Biochemistry, Friedrich-Schiller-University Jena
2001 apl Professor of Neurochemistry at Dept. Epileptology, Bonn University, School of Medicine
1998 Division of Neurochemistry, Department of Epileptology, Bonn University
1994–1997 Head of Neurobiochemistry Lab., Department Neurology, Magdeburg University
1992–1994 Head of Neurobiochemistry Group, Institute of Biochemistry, Magdeburg University
1983–1992 Research assistant, Institute of Biochemistry, Magdeburg University
1989–1990 Visiting Assistant Professor of Biochemistry, Medical School of Indiana University, Indianapolis

 

Miscellaneous
1989–1990 Fulbright fellowship
1994 Sandoz Price for Therapeutic Research

 

Selected Publications

Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, Kley RA, Barkovits K, Strecker V, Berwanger C, Herrmann H, Marcus K, Kornblum C, Kunz WS, Schröder R, Clemen CS. (2016) Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue. Acta Neuropathol 132:453–473. (IF: 11.360)

Volmering E, Niehusmann P, Peeva V, Grote A, Zsurka G, Altmüller J, Nürnberg P, Becker AJ, Schoch S, Elger CE, Kunz WS. (2016) Neuropathological signs of inflammation correlate with mitochondrial DNA deletions in mesial temporal lobe epilepsy. Acta Neuropathol 132:277–288. (IF: 11.360)

Lenk GM, Szymanska K, Debska-Vielhaber G, Rydzanicz M, Walczak A, Bekiesinska-Figatowska M, Vielhaber S, Hallmann K, Stawinski P, Buehring S, Hsu DA, Kunz WS, Meisler MH, Ploski R. (2016) Biallelic Mutations of VAC14 in Pediatric-Onset Neurological Disease. Am J Hum Genet 99:188–194. (IF: 10.794)

Hallmann K, Kudin AP, Zsurka G, Kornblum C, Reimann J, Stüve B, Waltz S, Hattingen E, Thiele H, Nürnberg P, Rüb C, Voos W, Kopatz J, Neumann H, Kunz WS. (2016) Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy. Brain 139:338–345. (IF: 10.103)

Zsurka G, Kunz WS. (2015) Mitochondrial dysfunction and seizures: the neuronal energy crisis. Lancet Neurol 14:956–966. (IF: 23.468)

Baris OR, Ederer S, Neuhaus JF, von Kleist-Retzow JC, Wunderlich CM, Pal M, Wunderlich FT, Peeva V, Zsurka G, Kunz WS, Hickethier T, Bunck AC, Stöckigt F, Schrickel JW, Wiesner RJ. (2015) Mosaic Deficiency in Mitochondrial Oxidative Metabolism Promotes Cardiac Arrhythmia during Aging. Cell Metab 21:667–677. (IF: 17.303)

Kornblum C, Nicholls TJ, Haack TB, Schöler S, Peeva V, Danhauser K, Hallmann K, Zsurka G, Rorbach J, Iuso A, Wieland T, Sciacco M, Ronchi D, Comi GP, Moggio M, Quinzii CM, DiMauro S, Calvo SE, Mootha VK, Klopstock T, Strom TM, Meitinger T, Minczuk M, Kunz WS*, Prokisch H. (2013) Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. Nat Genet 45:214–219. (IF: 31.616)
*corresponding author

Vielhaber S, Debska-Vielhaber G, Peeva V, Schoeler S, Kudin AP, Minin I, Schreiber S, Dengler R, Kollewe K, Zuschratter W, Kornblum C, Zsurka G, Kunz WS. (2013) Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion. Acta Neuropathol 125:245–256. (IF: 11.360)

Zsurka G, Kraytsberg Y, Kudina T, Kornblum C, Elger CE, Khrapko K, Kunz WS. (2005) Recombination of mitochondrial DNA detected in skeletal muscle of individuals with multiple mitochondrial DNA heteroplasmy. Nat Genet 37:873–877. (IF: 31.616)

Kraytsberg Y, Schwartz M, Brown TA, Ebralidse K, Kunz WS, Clayton DA, Vissing J, Khrapko K. (2004) Recombination of human mitochondrial DNA. Science 304:981. (IF: 34.661)