IEECR

Publications

2018

N.M., Beckonert, T., Opitz, J., Pitsch, P., da Silva, H., Beck, (2018) Polyamine Modulation of Anticonvulsant Drug Response: A Potential Mechanism Contributing to Pharmacoresistance in Chronic Epilepsy. J. Neuroscience 38: 5596-5605 (PubMed)

A.J., Becker, H., Beck, (2018) New developments in understanding focal cortical malformations. Curr. Opin. Neurobiol. 31: 151-155 (pdf)

O., Braganza, H., Beck, (2018) The circuit motif as conceptual tool for multilevel neuroscience. Trends Neurosci. 41: 128-136 (PubMed)


2017

T., Kelly, H., Beck, (2017) Functional properties of granule cells with hilar basal dendrites in the epileptic dentate gyrus. Epilepsia 58: 160-171 (PubMed)

D., Holtkamp, T., Opitz, I., Niespodziany, C., Wolf, H., Beck, (2017) Activity of the anticonvulsant lacosamide in experimental and human epilepsy via selective effects on slow Na+ channel inactivation. Epilepsia 58: 27-41 (PubMed)

O., Taha, T., Opitz, M., Müller, J., Pitsch, A.., Becker, B.O., Evert, H., Beck, M., Jeub, (2017) Neuropathic pain in experimental autoimmune neuritis is associated with altered electrophysiological properties of nociceptive DRG neurons. Exp. Neurol. 297: 25-35 (PubMed)


2016

M., Pabst, O., Braganza, H., Dannenberg, W., Hu, L., Pothmann, J., Rosen, I., Mody, K., van Loo, K., Deisseroth, A.J., Becker, S., Schoch, H., Beck, (2016) Astrocyte intermediaries of septal cholinergic modulation in the hippocampus.. Neuron 9: ec126- (PubMed) Featured in: Science Signalling, Editors Choice. (2016) Astrocytes help make memories.

A., Pitkänen, W., Löscher, A., Vezzani, A.J., Becker, M., Simonanto, K., Lukasiuk, O., Gröhn, J.P., Bankstahl, A., Friedmann, E., Aronica, J.A., Gorter, T., Ravizza, S.M., Sisodiya, M., Kokaia, H., Beck, (2016) Advances in the development of biomarkers for epilepsy. Lancet Neurol. 15: 843-856 (pdf)


2015

S., Lennarz, T.C., Alich, T., Kelly, M., Blind, H., Beck, (2015) Selective aptamer-based control of intraneuronal signaling. Angew. Chemie 54: 5369-5373 (PubMed)

H., Dannenberger, M., Pabst, O., Braganza, S., Schoch, J., Niediek, M., Bayraktar, F., Mormann, H., Beck, ., , (2015) Synergy of direct and indirect cholinergic septo-hippocampal pathways coordinates firing in hippocampal networks. J. Neuroscience 35: 8394-5373 (PubMed)

A., Kabanova, M., Pabst, M., Lorokowsky, O., Braganza, A., Boehlen, N., Nikbakht, L., Pothmann, A.R., Vaswani, R., Musgrove, D.A., Di Monte, M., Sauvage, H., Beck, (2015) Function and developmental origin of a mesocortical inhibitory circuit. Nat. Neurosci. 18: 872-882 (PubMed)

K.M.J., van Loo, C., Schaub, J., Pitsch, R., Kulbirda, T., Opitz, D., Ekstein, A., Dalal, H., Urbach, H., Beck, Y., Yari, S., Schoch, A.J., Becker, (2015) Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1. Nature Comm. 6: 8688- (pdf)

M., Royeck, T., Kelly, T., Opitz, D.M., Otte, A., Rennhack, A., Woitecki, J., Pitsch, A., Becker, S., Schoch, U.B., Kaupp, Y., Yaari, A., Zimmer, H., Beck, (2015) Downregulation of spermine augments dendritic persistent sodium currents and synaptic integration after status epilepticus. J. Neuroscience 35: 15240-15253 (PubMed)


2014

B., Pabier, M., Jeub, A., Markert, D., Mauer, K., Tolksdorf, T., Van de Putte, E., Seuntjens, V., Gailus-Durner, H., Fuchs, M., Jeub, M., Hrabě de Angelis, D., Huylebroeck, H., Beck, A., Zimmer, I., Rácz, (2014) Smad-interacting protein 1 affects acute and tonic, but not chronic pain. Eur. J. Pain 18: 249-257 (PubMed)

A., Doeser, P., Soares-da-Silva, H., Beck, M., Uebachs, (2014) The effects of eslicarbazepine on persistent Na⁺ current and the role of the Na⁺ channel β subunits. Epilepsy Res. 108: 202-211 (PubMed)

L., Pothmann, C., Müller, R.G., Averkin, E., Bellistri, C., Miklitz, M., Uebachs, S., Remy, M.L., de la Prida, H., Beck, (2014) Function of inhibitory micronetworks is spared by Na+ channel-acting anticonvulsant drugs. J. Neuroscience 34: 9720-9735 (PubMed)

C., Thome, T., Kelly, A., Yanez, C., Schultz, M., Engelhardt, S.B., Campbridge, M., Both, A., Draguhn, H., Beck, A.V., Egorov, (2014) Axon-carrying dendrites convey privileged synaptic input in hippocampal neurons. Neuron 83: 1418-1430 (PubMed)

U.B., Hedrich, C., Liautard, D., Kirschbaum, M., Pofahl, J., Lavigne, Y., Liu, S., Theiss, (2014) Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human NaV1.1 mutation. J. Neuroscience 34: 14874-14889 (PubMed)

A., Doeser, G., Dickhof, M., Reitze, M., Uebachs, C., Schaub, N.M., Pires, M.J., Bonifácio, P., Soares da Silva, H., Beck, (2014) Targeting pharmacoresistant epilepsy and epileptogenesis with a dual-purpose antiepileptic drug. Brain 138: 371-387 (pdf)


2013

E., Alvarez-Baron, K., Michel, T., Mittelstaedt, T., Opitz, F., Schmitz, H., Beck, D., Dietrich, A.J., Becker, S., Schoch, (2013) RIM3γ and RIM4γ are key regulators of neuronal arborization. J. Neuroscience 33: 824-839 (PubMed)

K., Klatte, T., Kirschstein, D., Otte, L., Pothmann, L., Müller, T., Tokay, M., Kober, M., Uebachs, A., Zimmer, H., Beck, (2013) Impaired D-serine-mediated cotransmission mediates cognitive dysfunction in epilepsy. J. Neuroscience 33: 13066-13080 (PubMed)


2012

K.M., Van Loo, C., Schaub, K., Pernhorst, Y., Yari, H., Beck, S., Schoch, A.J., Becker, (2012) Transcriptional regulation of T-type calcium channel CaV3.2: bi-directionality by early growth response 1 (Egr1) and repressor element 1 (RE-1) protein-silencing transcription factor (REST). Bio. Chem. 287: 15489-15501 (PubMed)

R., Surges, M., Kukley, A., Brewster, C., Rüschenschmidt, J., Schramm, T.Z., Baram, H., Beck, D., Dietrich, (2012) Hyperpolarization-activated cation current Ih of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy. Biochem. Biophys. Res. Commun. 420: 156-160 (pdf)

C., Müller, H., Beck, D., Coulter, S., Remy, (2012) Inhibitory control of linear and supralinear dendritic excitation in CA1 pyramidal neurons. Neuron 75: 851-864 (PubMed)

J., Pitsch, T., Opitz, V., Borm, A., Woitecki, M., Staniek, H., Beck, A.J., Becker, S., Schoch, (2012) The presynaptic active zone protein RIM1α controls epileptogenesis following status epilepticus. J. Neuroscience 32: 12384-12395 (PubMed)

M., Uebachs, C., Albus, T., Opitz, L., Isom, I., Niespodziany, C., Wolf, H., Beck, (2012) Loss of β1 accessory Na+ channel subunits causes failure of carbamazepine, but not of lacosamide, in blocking high-frequency firing via differential effects on persistent Na+ currents. Epilepsia 53: 1959-1967 (PubMed)